# Maybe the placebo effect isn't real?

Incredibly, the placebo effect is (mostly) not real.

— Jonatan Pallesen (@jonatanpallesen) August 21, 2023

It is a result of statistical confusion. Whenever you have a group with extreme values, they tend to exhibit regression to the mean. Eg. on average, sick people tend to become more healthy over time.

Thus if you give one… https://t.co/1s0qddGgk4 pic.twitter.com/8AOqGbyGtl

A more compelling explanation than any other I've heard to date.

2023-08-21